Contemporary Drug Synthesis (2004)
Science / Chemistry / Industrial & Technical, - Science / Chemistry / General, - Science / Chemistry / Organic -
NOT_MATURE -
Jie Jack Li, Douglas S. Johnson, Drago R. Sliskovic, Bruce D. Roth
Overview
An integrated and insightful look at successful drug synthesis in today's drug discovery market <p>The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug.</p> <p><i>Contemporary Drug Synthesis</i> examines how leading researchers and manufacturers have integrated chemistry, biology, pharmacokinetics, and a host of other disciplines in the creation and development of leading drugs.</p> <p>Authored by four of the pharmaceutical industry's most respected scientists, this timely volume:</p> <ul> <li>Focuses on the processes that resulted in high-profile drugs including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and over a dozen others</li> <li>Provides an in-depth introduction to each drug, followed by a detailed account of its synthesis</li> <li>Organizes the drugs into fourteen therapeutic areas for clarity and ease of use</li> </ul> Process chemists provide an essential bridge between chemistry and the marketplace, creating scientifically practical drug processes while never losing sight of the commercial viability of those processes. <i>Contemporary Drug Synthesis</i> meets the needs of a growing community of researchers in pharmaceutical research and development, and is both a useful guide for practicing pharmaceutical scientists and an excellent text for medicinal and organic chemistry students.